Tyrosine Kinase Assays

ACD has developed the largest commercially available panel of isogenic cell-based protein tyrosine kinase assays. Consisting of 165 individual assays, there are multiple representatives of each protein tyrosine kinase sub-family as well as alternative fusion forms and mutant alleles (access information by clicking on the [M] hyperlink). Our assay panel provides a unique and powerful discovery tool for exploring compound activities, target cross-reactivities, and polymorphic conformer impact on small-molecule efficacy. These data not only aid in a more thorough understanding of compound properties, but they can also be instrumental in re-purposing abandoned candidates against one of the most important target class families in the pharmaceutical industry.

Registered users may click on the kinase of interest for additional information including biological properties and validation data. To gain access, please Register. Returning users please Sign In.

PTK7 Tyrosine Kinase Assay ABL2 Tyrosine Kinase Assay ROR1 Tyrosine Kinase Assay ROS1 Tyrosine Kinase Assay TEK Tyrosine Kinase Assay MERTK Tyrosine Kinase Assay AXL Tyrosine Kinase Assay ERBB2 Tyrosine Kinase Assay EGFR Tyrosine Kinase Assay CSF1R Tyrosine Kinase Assay FAK Tyrosine Kinase Assay ZAP70 Tyrosine Kinase Assay MST1R Tyrosine Kinase Assay NTRK2 Tyrosine Kinase Assay NTRK3 Tyrosine Kinase Assay NTRK1 Tyrosine Kinase Assay SYK Tyrosine Kinase Assay SRC Tyrosine Kinase Assay TYRO3 Tyrosine Kinase Assay RYK Tyrosine Kinase Assay TIE1 Tyrosine Kinase Assay MET Tyrosine Kinase Assay ALK Tyrosine Kinase Assay TYK2 Tyrosine Kinase Assay RET Tyrosine Kinase Assay PDGFRA Tyrosine Kinase Assay PDGFRB Tyrosine Kinase Assay LYN Tyrosine Kinase Assay LCK Tyrosine Kinase Assay KIT Tyrosine Kinase Assay VEGFR2 Tyrosine Kinase Assay JAK3 Tyrosine Kinase Assay JAK2 Tyrosine Kinase Assay JAK1 Tyrosine Kinase Assay INSR Tyrosine Kinase Assay IGF1R Tyrosine Kinase Assay VEGFR3 Tyrosine Kinase Assay FLT3 Tyrosine Kinase Assay VEGR1 Tyrosine Kinase Assay HCK Tyrosine Kinase Assay FRK Tyrosine Kinase Assay FGR Tyrosine Kinase Assay FGFR4 Tyrosine Kinase Assay FGFR3 Tyrosine Kinase Assay FGFR2 Tyrosine Kinase Assay FGFR1 Tyrosine Kinase Assay EphB4 Tyrosine Kinase Assay EphB2 Tyrosine Kinase Assay EphB1 Tyrosine Kinase Assay DDR2 Tyrosine Kinase Assay BLK Tyrosine Kinase Assay BTK Tyrosine Kinase Assay BMX Tyrosine Kinase Assay ABL Tyrosine Kinase Assay EphA5 Tyrosine Kinase Assay EphA4 Tyrosine Kinase Assay EphA1 Tyrosine Kinase Assay EphA3 Tyrosine Kinase Assay ITK Tyrosine Kinase ERBB3 Tyrosine Kinase Assay FYN Tyrosine Kinase Assay FLT3-ITD Tyrosine Kinase Assay Mutant ALK Tyrosine Kinase Assays Mutant EGFR Tyrosine Kinase Assays Mutant FGFR Tyrosine Kinase Assays Mutant FGFR Tyrosine Kinase Assays Mutant FGFR Tyrosine Kinase Assays Mutant FGFR Tyrosine Kinase Assays Mutant RET Tyrosine Kinase Assays Mutant FLT3-ITD Tyrosine Kinase Assays Mutant KIT Tyrosine Kinase Assays